| Actor | Character | Seasons | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | |||||
| Andrew Garfield | Chuck Salvatore | Main | Recurring | Main | |||||||
| Rachel Bilson | Anna Clarkson | Main | Recurring | Main | Recurring | Main | |||||
| Adamo Ruggiero | A.J. Riley | Main | Recurring | Main | |||||||
| Miranda Cosgrove | Addison Lee | Main | Recurring | Main | |||||||
| Luke Bilyk | Daniel Mick | Main | Guest | ||||||||
| Asher Book | Charlie Holden | Main | Recurring | Main | |||||||
| Lucy Hale | Elizabeth Moore | Main | Recurring | Main | |||||||
| Mischa Barton | Cheyenne McLarson | Main | Recurring | Main | |||||||
| Kellan Lutz | Rick Castello | Main | Guest | Main | |||||||
| Blake Lively | Claira Kingston | Main | Guest | Main | |||||||
| Matthew Morrison | Will Schuester | Main | Guest | ||||||||
| Drew Roy | Dougie Eastwood | Recurring | Main | ||||||||
| Jesse McCartney | Gunner White | Recurring | Main | Guest | Main | ||||||
| Cymphonique Miller | Carina Maraj | Main | Recurring | Main | |||||||
| Lucas Grabeel | Levi Lashane | Main | Recurring | Guest | |||||||
| Shanice Banton | Shannon Brockwood | Recurring | Main | Recurring | Main | ||||||
| Cam Gigandet | Clyde Andrews | Main | Guest | ||||||||
| Drake Bell | Denzil Mixx | Recurring | Main | ||||||||
| India Eisley | Candace Livingston | Recurring | Main | Guest | |||||||
| Francia Raisa | Isabel Almendarez | Recurring | Main | ||||||||
| Kendall Schmidt | Mayson Blackburn | Recurring | Main | Guest | |||||||
| Hayden Panettiere | Melody Green | Main | |||||||||
| Diego Boneta | Nathan Branth | Main | |||||||||
| Lindsey Shaw | Joanna Harrow | Main | |||||||||
| Jessica Szohr | Kaiden Rivers | Main | |||||||||
| Logan Henderson | Jude Lopez | Main | |||||||||
| Cierra Ramirez | Brandy McDonell-Gomez | Main | |||||||||
Season Two:[]
- Mischa Barton as Cheyenne McLarson
- Luke Bilyk as Daniel Mick
- Asher Book as Charlie Holden
- Miranda Cosgrove as Addison Lee
- Andrew Garfield as Chuck Salvatore
- Travis Garland as Shawn Dawson
- Lucas Grabeel as Levi Lashane
- Lucy Hale as Elizabeth Moore
- Blake Lively as Claira Kingston
- Jesse McCartney as Gunner White
- Cymphonique Miller as Carina Maraj
- Matthew Morrison as Will Schuester
- Autumn Reeser as Lily Stevens
- Drew Roy as Dougie Eastwood
- Adamo Ruggiero as A.J. Riley
Season Three:[]
- Shanice Banton as Shannon Brockwood
- Mischa Barton as Cheyenne McLarson
- Drake Bell as Denzil Mixx
- Rachel Bilson as Anna Clarkson
- Asher Book as Charlie Holden
- Miranda Cosgrove as Addison Lee
- Andrew Garfield as Chuck Salvatore
- Lucas Grabeel as Levi Lashane
- Lucy Hale as Elizabeth Moore
- Josh Hutcherson as Drew Coach
- Blake Lively as Claira Kingston
- Jesse McCartney as Gunner White
- Cymphonique Miller as Carina Maraj
- Matthew Morrison as Will Schuester
- Drew Roy as Dougie Eastwood
- Adamo Ruggiero as A.J. Riley
- Ashley Tisdale as Alex Monroe